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Peer-reviewed veterinary case report

Detection of chicken chapparvovirus 2 in chickens with hemorrhagic hepatitis in Japan.

Journal:
The Journal of veterinary medical science
Year:
2024
Authors:
Fujino, Kan et al.
Affiliation:
School of Veterinary Medicine · Japan

Abstract

Chicken chaphamaparvovirus causes diarrheal symptoms and can be detected in fecal samples. This study reports the detection of chicken chapparvovirus 2 in debilitated chickens with hemorrhagic hepatitis at a broiler farm in Japan. After euthanasia and necropsy, liver hemorrhage was observed. Nuclear inclusion bodies in the hepatocytes were identified using histological analysis. High-throughput sequencing analysis using RNA from livers of three affected chickens revealed infection by chicken chapparvovirus 2 and chicken anemia virus. Polymerase chain reaction analysis showed that all three chickens were positive for chicken chapparvovirus 2, and only one was positive for both chicken chapparvovirus 2 and chicken anemia virus. In conclusion, chicken chapparvovirus 2 causes infection in chickens in Japan and might be involved in hemorrhagic hepatitis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38346726/