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Peer-reviewed veterinary case report

Detection of foot-and-mouth disease serotype O by ELISA using a monoclonal antibody.

Journal:
Monoclonal antibodies in immunodiagnosis and immunotherapy
Year:
2013
Authors:
Chen, Hao-Tai et al.
Affiliation:
College of Veterinary Medicine · China

Abstract

An ELISA assay with monoclonal antibody (MELISA) was used to type serotype O of foot-and-mouth disease virus (FMDV). All FMDV serotype O reference strains were positive by MELISA, while other viruses such as FMDV serotypes Asia 1, C, and A and classical swine fever virus, swine vesicular disease virus, and porcine reproductive and respiratory syndrome virus remained negative. Furthermore, FMDV serotype O positive samples were able to be detected by MELISA. This assay may be particularly suitable for diagnosis of FMDV serotype O infection in field stations.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23600506/