Peer-reviewed veterinary case report
Canine parvovirus 2c found in Australian dogs with vomiting
By Woolford, Lucy et al.·Published in Viral immunology·2017·1 School of Animal and Veterinary Sciences, Australia·View original on PubMed →
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Original publication title: Detection of the Canine Parvovirus 2c Subtype in Australian Dogs.
- Species:
- dog
Plain-English summary
An 8-week-old puppy died from severe vomiting and bloody diarrhea caused by a new strain of canine parvovirus (CPV-2c) in Australia. Two other dogs, an 11-month-old Saint Bernard and a 9-month-old Siberian husky, showed milder symptoms like vomiting and diarrhea despite being fully vaccinated. Genetic testing confirmed that all three cases were linked to this new variant of the virus. This finding highlights the importance of awareness among veterinarians, as CPV-2c is now present in the Australian dog population, affecting both puppies and vaccinated dogs.
People also search for: puppy vomiting diarrhea · parvovirus in vaccinated dogs · Saint Bernard vomiting treatment
Abstract
Canine parvovirus (CPV-2) is an important cause of hemorrhagic enteritis in dogs. In Australia the disease has been associated with CPV-2a and CPV-2b variants. A third more recently emerged variant overseas, CPV-2c, has not been detected in surveys of the Australian dog population. In this study, we report three cases of canine parvoviral enteritis associated with CPV-2c infection; case 1 occurred in an 8-week-old puppy that died following acute hemorrhagic enteritis. Cases 2 and 3 were an 11-month-old female entire Saint Bernard and a 9-month-old male entire Siberian husky, respectively, both which had completed vaccination schedules and presented with vomiting or mild diarrhea only. Full genomic sequencing of parvoviral DNA from cases 1, 2, and 3 revealed greater than 99% homology to known CPV-2c variants and predicted protein sequences from the VP2 region of viral DNA from all three cases identified; glutamic acid residues at the 426 amino acid residue, characteristic of the CPV-2c variant. Veterinary professionals should be aware that CPV-2c is now present in Australia, detected in a puppy and vaccinated young adult dogs in this study. Further characterization of CPV-2c-associated disease and its prevalence in Australian dogs requires additional research.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28414634/