Peer-reviewed veterinary case report
Canine distemper virus found in Turkish dogs with nervous symptoms
By Ozkul, A et al.·Published in Acta veterinaria Hungarica·2004·Department of Virology·View original on PubMed →
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Original publication title: Determination and phylogenetic analysis of canine distemper virus in dogs with nervous symptoms in Turkey.
- Species:
- dog
Plain-English summary
A group of 20 dogs in Turkey showing nervous symptoms was tested for canine distemper virus (CDV), a serious illness that can affect the nervous system. Most of these dogs were strays with no vaccination records, and many displayed both nervous and mild respiratory symptoms. Testing revealed that 45% of the dogs had CDV, and the immune response in most cases was not strong enough to effectively fight the virus. This suggests that either previous vaccinations were ineffective or the dogs had mild infections. Treatment options for CDV can vary, and it's crucial to consult a veterinarian for the best care.
People also search for: dog nervous symptoms · canine distemper treatment · stray dog vaccination status · dog respiratory distress · CDV in dogs
Abstract
In the present study, canine distemper virus (CDV) was investigated in 20 dogs having nervous signs arousing the clinical suspicion of canine distemper (CD). A total of 13 animals (65%) were stray dogs and had no accurate record about the vaccination history. Clinical examinations revealed that the majority (85%) of the animals showed systemic form characterised by predominantly nervous symptoms accompanied by mild respiratory system signs whilst the remaining cases (15%) recorded mainly respiratory distress. CDV RNA was detected by reverse transcription-polymerase chain reaction (RT-PCR) only in 45% of the suspected cases. Phylogenetic analysis of partial nucleotide sequence of the P gene coding region revealed that the virus is closely related to European strains. Immune responses in 13 cases (65%), which were detected by dot-ELISA, indicated inefficient levels for neutralising functions against CDV. It was postulated that this response could have been mediated by either previous vaccination or mild infection with field strains.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15119793/