Peer-reviewed veterinary case report
Serum pancreatic lipase levels in cats with diabetes mellitus
By Forcada, Yaiza et al.·Published in Journal of Feline Medicine and Surgery·2008·Department of Veterinary Clinical Science, University of Liverpool, Leahurst, UK, United Kingdom·View original on Crossref →
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Original publication title: Determination of serum fPLI concentrations in cats with diabetes mellitus
- Species:
- cat
Plain-English summary
A group of 29 cats with diabetes mellitus (DM) had their blood tested for a specific marker (fPLI) that indicates pancreatitis, a condition that can complicate diabetes. The results showed that the diabetic cats had significantly higher fPLI levels compared to 23 non-diabetic cats of similar age. This suggests that pancreatitis might be a common issue in diabetic cats, even if they don't show obvious symptoms. Understanding this connection can help veterinarians better manage diabetic cats and address any underlying pancreatitis.
People also search for: cat diabetes symptoms · pancreatitis in diabetic cats · high fPLI levels in cats · managing cat diabetes and pancreatitis
Abstract
Diabetes mellitus (DM) is one of the most common feline endocrinopathies. Pancreatitis is a reported cause for poor control of DM in cats; however, its prevalence in diabetic cats is unknown. Measurement of serum feline pancreatic lipase immunoreactivity (fPLI) has been proposed as a sensitive and specific test for the detection of pancreatitis in cats. The aim of this study was to assess fPLI concentrations in diabetic cats and compare these with non-diabetic cats of similar age. Samples from 29 cats with DM and 23 non-diabetic cats were analysed. Serum fPLI concentrations were significantly higher in samples from diabetic cats ( P<0.01). A weak association was found between serum fructosamine and fPLI concentrations ( R 2 =0.355, P=0.015), but there was no association between fPLI concentrations and the degree of diabetic control. There were no significant differences in reported clinical signs between cats with or without DM regardless of serum fPLI concentration. This is the first study to demonstrate elevated serum fPLI concentrations in cats with DM, suggesting that pancreatitis could be a significant comorbidity in these cats.
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Search related cases →Original publication on Crossref: https://doi.org/10.1016/j.jfms.2007.04.007