Peer-reviewed veterinary case report
Serum pancreatic lipase levels in cats with diabetes mellitus
By Forcada, Yaiza et al.·Published in Journal of feline medicine and surgery·2008·Department of Veterinary Clinical Science, United Kingdom·View original on PubMed →
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Original publication title: Determination of serum fPLI concentrations in cats with diabetes mellitus.
- Species:
- cat
Plain-English summary
A group of 29 cats with diabetes was tested for pancreatitis using a specific blood test that measures a substance called fPLI. The results showed that these diabetic cats had higher fPLI levels compared to 23 non-diabetic cats, indicating that pancreatitis might be a common issue for cats with diabetes. However, the study found no clear link between the severity of diabetes control and fPLI levels, nor were there noticeable differences in symptoms between the two groups. This suggests that if your diabetic cat is not doing well, pancreatitis could be a factor to discuss with your veterinarian.
People also search for: cat diabetes symptoms · pancreatitis in diabetic cats · fPLI test for cats · managing cat diabetes and pancreatitis
Abstract
Diabetes mellitus (DM) is one of the most common feline endocrinopathies. Pancreatitis is a reported cause for poor control of DM in cats; however, its prevalence in diabetic cats is unknown. Measurement of serum feline pancreatic lipase immunoreactivity (fPLI) has been proposed as a sensitive and specific test for the detection of pancreatitis in cats. The aim of this study was to assess fPLI concentrations in diabetic cats and compare these with non-diabetic cats of similar age. Samples from 29 cats with DM and 23 non-diabetic cats were analysed. Serum fPLI concentrations were significantly higher in samples from diabetic cats (P<0.01). A weak association was found between serum fructosamine and fPLI concentrations (R(2)=0.355, P=0.015), but there was no association between fPLI concentrations and the degree of diabetic control. There were no significant differences in reported clinical signs between cats with or without DM regardless of serum fPLI concentration. This is the first study to demonstrate elevated serum fPLI concentrations in cats with DM, suggesting that pancreatitis could be a significant comorbidity in these cats.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18639478/