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Peer-reviewed veterinary case report

New rapid antibody test detects Babesia gibsoni infection in dogs

By Jia, Honglin et al.·Published in Parasitology research·2007·Obihiro University of Agriculture and Veterinary Medicine, Japan·View original on PubMed

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Original publication title: Development of an immunochromatographic test with recombinant BgSA1 for the diagnosis of Babesia gibsoni infection in dogs.

Species:
dog

Plain-English summary

A group of dogs in Japan was tested for Babesia gibsoni infection, which can cause serious health issues. Researchers developed a new, quick test that can detect specific antibodies in dogs infected with this parasite. Out of 94 dogs tested, about 22% showed positive results for the infection using this new test, and it matched well with an existing testing method. This new test is promising because it is fast and accurate, making it easier for vets to diagnose Babesia gibsoni infections in dogs.

People also search for: dog Babesia gibsoni symptoms · quick test for dog infections · how to diagnose Babesia in dogs

Abstract

An immunochromatographic test (ICT) using recombinant BgSA1 (rBgSA1) for the detection of antibodies against Babesia gibsoni was developed and evaluated. Only the serum samples collected from dogs infected with B. gibsoni were positive in the ICT, but the serum samples from dogs infected with closely related parasites and from healthy dogs were negative. The specific antibodies could be detected in a dog experimentally infected with B. gibsoni at both the acute and chronic infection stages by the ICT. To evaluate the clinical application of the ICT, a total of 94 serum samples collected from domestic dogs in Japan were tested with the ICT and the previously established enzyme-linked immunosorbent assay (ELISA) with rBgSA1. Twenty-one of the tested samples (22.3%) were positive in both the ICT and the ELISA. The concordance between the ELISA and the ICT was found to be 95.8%. These results suggested that the ICT using rBgSA1 is rapid, simple, accurate, and suitable for the diagnosis of B. gibsoni infection of dogs in the field.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17171565/