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Peer-reviewed veterinary case report

Diabetic ketoacidosis and hyperosmolar state in cats

By Rand, Jacquie S·Published in The Veterinary clinics of North America. Small animal practice·2013·School of Veterinary Science, Australia·View original on PubMed

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Original publication title: Diabetic ketoacidosis and hyperosmolar hyperglycemic state in cats.

Species:
cat

Plain-English summary

A cat with diabetes can develop serious conditions like diabetic ketoacidosis or hyperosmolar hyperglycemic state, which can be life-threatening. Symptoms may include loss of appetite, vomiting, and in severe cases, even coma. These issues arise from a lack of insulin and can lead to dehydration and other health problems. Treatment focuses on providing fluids and electrolytes, managing any other illnesses, and restoring insulin levels. Early diagnosis and proper insulin treatment for diabetes can help prevent these dangerous complications.

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Abstract

Diabetic ketoacidosis and hyperosmolar hyperglycemic state are 2 potentially life-threatening presentations of feline diabetes mellitus. Presentations range from mildly anorexic cats with diabetic ketoacidosis to comatose cats with diabetic ketoacidosis or hyperosmolar hyperglycemic state. Such cases are the result of severe insulin deficiency and/or concurrent disease, resulting in nausea and vomiting, electrolyte and water losses, acidosis, and circulatory collapse. The condition requires careful attention to supportive care to correct fluid and electrolyte abnormalities, treatment of concurrent diseases, and reversal of the effects of insulin deficiency. However, early diagnosis of diabetes mellitus and institution of appropriate insulin therapy prevents these complications.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23522177/