Peer-reviewed veterinary case report
Diagnosis of pancreatitis in dogs and cats.
- Journal:
- The Journal of small animal practice
- Year:
- 2015
- Authors:
- Xenoulis, P G
- Affiliation:
- Clinic of Medicine
Plain-English summary
Pancreatitis, which is an inflammation of the pancreas, is a common issue in both dogs and cats. Diagnosing it can be tricky because the symptoms can range from mild to severe and are often vague. If your pet is suspected of having pancreatitis, your veterinarian will likely run blood tests and a urinalysis, but these tests alone may not confirm the condition. The best test for diagnosing pancreatitis is measuring a specific enzyme called pancreatic lipase in the blood. While imaging tests like X-rays and ultrasounds can help rule out other problems, the most reliable way to diagnose pancreatitis involves looking at your pet's history, the pancreatic lipase test, and sometimes further examination of the pancreas itself.
Abstract
Pancreatitis is the most common disorder of the exocrine pancreas in both dogs and cats. Ante-mortem diagnosis of canine and feline pancreatitis can be challenging. The clinical picture of dogs and cats with pancreatitis varies greatly (from very mild to severe or even fatal) and is characterised by non-specific findings. Complete blood count, serum biochemistry profile and urinalysis should always be performed in dogs and cats suspected of having pancreatitis, although findings are not-specific for pancreatitis. Serum amylase and lipase activities and trypsin-like immunoreactivity (TLI) concentrations have no or only limited clinical value for the diagnosis of pancreatitis in either dogs or cats. Conversely, serum pancreatic lipase immunoreactivity (PLI) concentration is currently considered to be the clinicopathological test of choice for the diagnosis of canine and feline pancreatitis. Abdominal radiography is a useful diagnostic tool for the exclusion of other diseases that may cause similar clinical signs to those of pancreatitis. Abdominal ultrasonography can be very useful for the diagnosis of pancreatitis, but this depends largely on the clinician's experience. Histopathological examination of the pancreas is considered the gold standard for the diagnosis and classification of pancreatitis, but it is not without limitations. In clinical practice, a combination of careful evaluation of the animal's history, serum PLI concentration and abdominal ultrasonography, together with pancreatic cytology or histopathology when indicated or possible, is considered to be the most practical and reliable means for an accurate diagnosis or exclusion of pancreatitis compared with other diagnostic modalities.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25586803/