Peer-reviewed veterinary case report
How biopsy cytology helps diagnose gut problems in dogs and cats
By Ruiz, G et al.·Published in The Journal of small animal practice·2017·Université, France·View original on PubMed →
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Original publication title: Diagnostic contribution of cytological specimens obtained from biopsies during gastrointestinal endoscopy in dogs and cats.
Plain-English summary
A group of 18 dogs and 5 cats with ongoing stomach or intestinal issues underwent endoscopy to help diagnose their problems. During the procedure, two different techniques were used to collect samples from the gastrointestinal tract: the "imprint" and "squash" methods. The squash technique was found to provide better samples for analysis, allowing for a correct diagnosis in 65% of cases when compared to the traditional histology method. This suggests that using the squash technique can give veterinarians important additional information to help identify issues in pets with gastrointestinal symptoms.
People also search for: dog gastrointestinal problems diagnosis · cat endoscopy results · squash technique cytology pets
Abstract
OBJECTIVES: The aims of this study were to compare cytological samples obtained from endoscopic biopsies using "imprint" and "squash" techniques, and to evaluate the potential value of cytology compared to histology in reaching the diagnosis. MATERIALS AND METHODS: Eighteen dogs and five cats undergoing endoscopy for chronic gastrointestinal signs were prospectively included. Imprint and squash samples were obtained from one biopsy and then analysed. Comparison between cytology and histology was performed using Cohen's j coefficient. RESULTS: Appropriate samples for cytological evaluation were more often obtained with the squash technique (96% of the cases versus 68% with the imprint technique). The diagnoses obtained with cytological samples and by histology, considered as the gold standard, were compared. The same diagnosis was obtained with the squash technique in 65% of the cases. Furthermore, cytology was considered complementary to histology for gastric spiral organisms and mast cells identification. CLINICAL SIGNIFICANCE: These results suggest that squash cytology obtained from endoscopic biopsies of the gastrointestinal tract can provide relevant and additional information to histology in dogs and cats.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27861922/