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Peer-reviewed veterinary case report

Cat with multiple red skin lumps that rupture and crust over

By Gelberg, H B·Published in Veterinary pathology·2013·Department of Biomedical Sciences, United States·View original on PubMed

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Original publication title: Diagnostic exercise: Multiple skin nodules in a cat.

Species:
cat

Plain-English summary

A 10-year-old male domestic short-haired cat developed multiple small, firm, red nodules all over his body that appeared suddenly and ruptured within two days, forming crusts. The veterinarian removed one of the nodules from his leg for testing, which revealed a specific type of skin condition called feline progressive epitheliotropic dendritic cell histiocytosis. This condition is characterized by abnormal growth of certain skin cells. The cat's treatment plan would typically involve monitoring and possibly medication to manage the symptoms, but specific outcomes weren't detailed in the study.

People also search for: cat skin nodules · feline progressive epitheliotropic dendritic cell histiocytosis · cat skin problems treatment

Abstract

A 10-year-old, neutered, male, domestic short-haired cat had numerous, small, firm, round, red, nonpruritic, nonpainful, dermal nodules 5-16 mm in diameter that ruptured within 48 hours of their appearance and subsequently crusted over. The masses were located in all regions of the body. One mass was excised from the dorsal right carpus and examined histologically, and 2 masses from the interscapular region were cultured for bacteria. The excised dermal mass from the carpus effaced normal dermal architecture, pressed tightly against the epidermis, and was composed of tightly packed round to polyhedral cells that extended to the deep margins of the sections. The overlying epidermis was extensively ulcerated and vesiculated with intraepidermal nests of cells identical to those in the dermis. There was marked anisokaryosis in the deeper regions of the mass with numerous multinucleated cells and cells with giant bizarre nuclei. The histological appearance and CD18 immunocytochemical staining of this mass are consistent with a diagnosis of feline progressive epitheliotropic dendritic cell histiocytosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23435572/