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Peer-reviewed veterinary case report

Diagnostic exercise: poor performance in a racehorse.

Journal:
Veterinary pathology
Year:
2014
Authors:
Giannitti, F et al.
Affiliation:
School of Veterinary Medicine · United States
Species:
horse

Abstract

A 9-year-old Thoroughbred gelding presented with a 97-day history of poor performance and intermittent fever. Clinicopathologic changes included increased serum activity of γ-glutamyltransferase and alkaline phosphatase, mild hyperbilirubinemia, and leukocytosis with neutrophilia and lymphopenia. Abdominal ultrasound revealed hepatomegaly with hyperechoic hepatic parenchyma and biliary distention. Pathologic findings included marked hepatomegaly (liver 3.6% of body weight), firm hepatic consistency with a diffuse enhanced reticular pattern, severe portal bridging and sinusoidal fibrosis, oval cell/bile duct hyperplasia, and bile stasis. The differential diagnoses and diagnostic workup to achieve the diagnosis are briefly discussed.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23610216/