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Peer-reviewed veterinary case report

Differences in blood protein patterns in dogs with Babesia gibsoni

By Tóthová, Csilla et al.·Published in Scientific reports·2020·Clinic of Ruminants·View original on PubMed

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Original publication title: Differences in serum protein electrophoretic pattern in dogs naturally infected with Babesia gibsoni and Babesia canis.

Species:
dog

Plain-English summary

A group of dogs infected with different types of Babesia parasites showed varying changes in their blood protein levels. Dogs infected with Babesia gibsoni had higher total protein levels but lower albumin levels compared to those infected with Babesia canis. These differences in blood tests suggest that the two types of infections affect dogs differently. Understanding these variations can help veterinarians provide better treatment based on the specific Babesia infection a dog has.

People also search for: dog Babesia infection symptoms · Babesia gibsoni vs Babesia canis treatment · dog blood test results interpretation

Abstract

Canine babesiosis may cause several hematological and biochemical changes, but only limited studies are available regarding the possible differences of changes in animals infected by different Babesia parasites. The study focused on the evaluation of the differences in serum protein electrophoretic pattern between dogs naturally infected with B. gibsoni (17 dogs) and B. canis (40 dogs). The mean values of total proteins, &#x3b2;-, &#x3b2;- and &#x3b3;-globulins were in dogs infected with B. gibsoni significantly higher (P&#x2009;<&#x2009;0.05 and P&#x2009;<&#x2009;0.001) than in dogs infected with B. canis. The relative concentrations of albumin, &#x3b1;-, &#x3b1;-globulins and the A/G ratios were in the B. gibsoni infected dogs significantly lower (P&#x2009;<&#x2009;0.001), no significant differences were found in the relative concentrations of &#x3b2;- and &#x3b2;-globulins. Significant differences were found in most of the evaluated parameters when comparing the results in relation to the form of B. canis infection to B. gibsoni infection. Hematological indices showed significant differences between dogs infected with B. gibsoni and the complicated form of B. canis infection. In conclusion, the obtained results suggest differences in the changes of serum protein electrophoretic pattern between dogs infected with both Babesia species and thus, in the response to the infection caused by various Babesia parasites.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33144631/