Peer-reviewed veterinary case report
Diffuse Large B-Cell Lymphoma in a Cynomolgus Monkey.
- Journal:
- Journal of medical primatology
- Year:
- 2024
- Authors:
- Li, Heling et al.
- Affiliation:
- Institute of Primate Translational Medicine · China
Abstract
A captive 17-year-old male cynomolgus monkey (Macaca fascicularis) developed diffuse large B-cell lymphoma (DLBCL). This was the first report of DLBCL presenting with a mandible mass and violation of the paranasal sinus in a cynomolgus monkey. The neoplasm showed marked microscopical malignant aspects. Immunohistochemical staining showed strong positive expression of CD20. These features may contribute to the diagnosis and therapeutics of DLBCL in NHPs.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/39245882/