Peer-reviewed veterinary case report
Shiba dog with lung nodules causing labored breathing
By Michishita, M et al.·Published in Journal of comparative pathology·2019·Department of Veterinary Pathology, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Diffuse Pulmonary Meningotheliomatosis with Sarcomatous Transformation in a Shiba Dog.
- Species:
- dog
Plain-English summary
A 2-year-old neutered female Shiba dog was having trouble breathing for a month. After a CT scan, the vet found multiple small nodules in her lungs. These nodules were firm and abnormal, leading to a diagnosis of diffuse pulmonary meningotheliomatosis with sarcomatous transformation, a rare lung condition. Unfortunately, the specific treatment and outcome for this case were not detailed, but the findings highlight a serious lung issue that requires veterinary attention.
People also search for: dog breathing problems · Shiba Inu lung nodules · dog lung disease treatment
Abstract
A 2-year-old neutered female Shiba dog exhibited laboured breathing for 1 month. Computed tomography of the thoracic cavity revealed multiple nodules (2-5 mm diameter) in the lungs. Grossly, the lungs were firm and normal in shape. The nodules were grey-white in colour. Microscopically, the nodules were non-encapsulated and exhibited an irregular shape. They were composed of polygonal or spindle cells with indistinct cell borders arranged in sheets. The cells had large, round, hyperchromatic nuclei and abundant pale eosinophilic cytoplasm with no atypia. Intrapulmonary arterial emboli and infiltration into the bronchioles were observed. Immunohistochemically, the cells were positive for vimentin and negative for cytokeratin, glial fibrillary acidic protein and α-smooth muscle actin. Ultrastructurally, the cells displayed cytoplasmic processes, desmosomes and intermediate filaments. These findings led to a diagnosis of diffuse pulmonary meningotheliomatosis with sarcomatous transformation. To the best of our knowledge, this is the first report of diffuse pulmonary meningotheliomatosis in a dog.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31540619/