Peer-reviewed veterinary case report
Dihydro-[1H]-quinolin-2-ones as retinoid X receptor (RXR) agonists for potential treatment of dyslipidemia.
- Journal:
- Bioorganic & medicinal chemistry letters
- Year:
- 2007
- Authors:
- Lagu, Bharat et al.
- Affiliation:
- Johnson and Johnson Pharmaceutical Research and Development · United States
Abstract
A number of RXR modulators with novel structural features were synthesized and screened in the functional assays. The synthesis and the structure-activity relationship within the series of compounds will be presented. Some in vivo data generated in the models for dyslipidemia and diabetes will also be presented.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17490875/