Peer-reviewed veterinary case report
Dimethyloxalylglycine may be enhance the capacity of neural-like cells in treatment of Alzheimer disease.
- Journal:
- Cell biology international
- Year:
- 2016
- Authors:
- Ghasemi Moravej, Fahimeh et al.
- Affiliation:
- Department of Anatomy
- Species:
- rodent
Abstract
Although using differentiated stem cells is the best proposed option for the treatment of Alzheimer disease (AD), an efficient differentiation and cell therapy require enhanced cell survival and homing and decreased apoptosis. It seems that hypoxia preconditioning via Dimethyloxalylglycine (DMOG) may increase the capacity of MSC to induce neural like stem cells (NSCs). Furthermore, it can likely improve the viability of NSCs when transplanted into the brain of AD rats.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27005959/