Peer-reviewed veterinary case report
Direct Immunoelectron Microscopy of Transmissible Gastroenteritis Virus with Immunoglobulins G and A and Guinea Pig Complement
- Journal:
- American Journal of Veterinary Research
- Year:
- 1980
- Authors:
- Jensen, M. T. et al.
- Affiliation:
- From the National Animal Disease Center, Agricultural Research, Science and Education Administration, US Department of Agriculture, Ames, IA 50010.
- Species:
- rodent
Abstract
SUMMARY Porcine colostral immunoglobulin (Ig)G and IgA, isolated from transmissible gastroenteritis virus-infected sows, were compared by direct immunoelectron microscopy. It was estimated, using antibodies with a less than a twofold difference in virus-neutralizing activity, that IgG was 500 times more efficient than was IgA for coating transmissible gastroenteritis virions. Guinea pig complement enhanced the antibody coating with IgG, but did not increase virus-neutralizing activity of IgG or IgA.
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Search related cases →Original publication: https://doi.org/10.2460/ajvr.1980.41.01.136