Peer-reviewed veterinary case report
Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist.
- Journal:
- Bioorganic & medicinal chemistry letters
- Year:
- 2011
- Authors:
- Hong, Qingmei et al.
- Affiliation:
- Department of Medicinal Chemistry · United States
Abstract
We report the discovery of piperazine urea based compound 1, a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist. Compound 1 shows anti-obesity efficacy without potentiating erectile activity in the rodent models.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21439820/