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Peer-reviewed veterinary case report

Female French bulldog with enlarged clitoris diagnosed with XX male

By Silversides, David W et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2011·Department of Veterinary Biomedicine, Canada·View original on PubMed

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Original publication title: Disorder of sex development (XX male, SRY negative) in a French bulldog.

Species:
dog

Plain-English summary

A female French bulldog was brought to the vet because she had an enlarged clitoris. During surgery, the vet found that her internal reproductive organs included a normal uterus and gonads that looked like testes. Further testing showed that she had an XX chromosome pattern and did not have the SRY gene, leading to a diagnosis of a rare condition called XX male, SRY negative disorder of sexual development. The outcome of the surgery and any follow-up treatment were not detailed in the study.

People also search for: French bulldog enlarged clitoris · dog sexual development disorder · XX male condition in dogs

Abstract

A female French bulldog was presented with an enlarged clitoris. Abdominal surgery revealed a normal uterus and gonads resembling testes. Histologically, the gonads contained seminiferous tubules. The karyotype was XX, and the SRY gene was not detected. A diagnosis of XX male, SRY negative disorder of sexual development was made.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22131587/