Peer-reviewed veterinary case report
Dog with fatal eosinophilic disease affecting heart and lungs
By Aroch, I et al.·Published in The Veterinary record·2001·Koret School of Veterinary Medicine·View original on PubMed →
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Original publication title: Disseminated eosinophilic disease resembling idiopathic hypereosinophilic syndrome in a dog.
- Species:
- dog
Plain-English summary
A 5-year-old mixed-breed dog was diagnosed with a serious condition involving high levels of a type of white blood cell called eosinophils, which infiltrated multiple organs, particularly the heart and lungs. The dog showed signs of organ dysfunction, and despite veterinary care, the condition led to a fatal outcome. This case highlights a rare disease in dogs that resembles a known syndrome in humans and cats, which can be difficult to treat and may have severe consequences.
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Abstract
True idiopathic hypereosinophilic syndrome has been described in human beings and cats, but not in dogs. The syndrome is characterised by prolonged unexplained peripheral mature eosinophilia, the infiltration of many organs by eosinophils, organ dysfunction and a fatal outcome. This paper describes an idiopathic disseminated eosinophilic disease in a dog involving various organs, manly the heart and the lungs, accompanied by a leukemoid eosinophilic response, and a fatal outcome. The histopathological findings included the infiltration of the myocardium, lung parenchyma, liver, spleen, lymph nodes and skeletal muscles with eosiniphils.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11601516/