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Peer-reviewed veterinary case report

Disseminated infection with Balamuthia mandrillaris in a dog.

Journal:
Veterinary pathology
Year:
2004
Authors:
Foreman, O et al.
Affiliation:
oded@vmth.ucdavis.edu
Species:
dog

Abstract

Bilateral chronic granulomatous nephritis and meningoencephalitis were diagnosed on necropsy of a 2-year-old male Great Dane dog. The causative agent was identified as Balamuthia mandrillaris, based on morphologic features, immunohistochemical staining, and deoxyribonucleic acid detection using the polymerase chain reaction with newly designed primer pairs. Trophozoite and cystic forms of the amoeba were evident within the kidneys and brain parenchyma. This is the first report on a B. mandrillaris infection in a dog.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15347823/