Peer-reviewed veterinary case report
Disseminated Balamuthia mandrillaris infection in a 2-year-old Great
By Foreman, O et al.·Published in Veterinary pathology·2004·oded@vmth.ucdavis.edu·View original on PubMed →
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Original publication title: Disseminated infection with Balamuthia mandrillaris in a dog.
- Species:
- dog
Plain-English summary
A 2-year-old male Great Dane was found to have serious health issues, including kidney and brain problems, after he passed away. A detailed examination revealed that he had a rare infection caused by a type of amoeba called Balamuthia mandrillaris. This infection led to severe inflammation in his kidneys and brain. Unfortunately, the dog did not survive, and this case marks the first known instance of this specific infection in dogs.
People also search for: Great Dane kidney infection · dog brain infection symptoms · Balamuthia mandrillaris in dogs
Abstract
Bilateral chronic granulomatous nephritis and meningoencephalitis were diagnosed on necropsy of a 2-year-old male Great Dane dog. The causative agent was identified as Balamuthia mandrillaris, based on morphologic features, immunohistochemical staining, and deoxyribonucleic acid detection using the polymerase chain reaction with newly designed primer pairs. Trophozoite and cystic forms of the amoeba were evident within the kidneys and brain parenchyma. This is the first report on a B. mandrillaris infection in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15347823/