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Peer-reviewed veterinary case report

Systemic fungal infection causing lethargy and vomiting

By Cohen, Jonathan & Johnson, Kryssa·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2025·Department of Radiology, United States·View original on PubMed

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Original publication title: Disseminated phaeohyphomycosis caused by Cladophialophora in an immunosuppressed cat.

Species:
cat

Plain-English summary

A 3-year-old female domestic shorthair cat was brought to the vet because she was very tired, not eating, vomiting, and had diarrhea. An ultrasound showed several abnormal nodules in her liver, kidneys, and pancreas. Tests revealed that these nodules were caused by a fungal infection from a type of fungus called Cladophialophora. The cat's immune system was already weakened due to previous treatment for anemia, which likely made her more susceptible to this infection. Treatment details weren't specified, but addressing the fungal infection is crucial for her recovery.

People also search for: cat vomiting and diarrhea · cat lethargy causes · fungal infection in cats treatment · domestic shorthair cat health issues

Abstract

A 3-year-old female spayed domestic shorthair cat with a history of immune-mediated hemolytic anemia, treated with cyclosporine and prednisolone, was presented for acute lethargy, anorexia, vomiting, and diarrhea. Abdominal ultrasound revealed multiple predominantly avascular hypo-anechoic nodules in the liver, kidneys, pancreas, and peritoneum. Fine needle aspirates and culture of the liver and kidney revealed abscessation caused by Cladophialophora. This case adds to the currently limited literature documenting ultrasonographic features of systemic infection caused by pigmented fungi in cats.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39431405/