Peer-reviewed veterinary case report
German Shepherd dog with widespread fungal kidney infection resistant
By Haynes, S M et al.·Published in Australian veterinary journal·2012·Small Animal Medicine Department, Australia·View original on PubMed →
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Original publication title: Disseminated Scedosporium prolificans infection in a German Shepherd dog.
- Species:
- dog
Plain-English summary
A 1-year-old female spayed German Shepherd was brought in with serious health issues caused by a widespread fungal infection. The dog showed signs of kidney problems, and tests revealed the fungus in her urine. Despite treatment with antifungal medications, including itraconazole and terbinafine, the infection proved resistant to all available drugs. Sadly, the dog's condition worsened, leading to her being euthanized due to severe abdominal bleeding and overall decline. A postmortem examination showed extensive damage from the infection throughout her body.
People also search for: German Shepherd fungal infection treatment · dog kidney problems symptoms · antifungal resistance in dogs
Abstract
Disseminated Scedosporium prolificans infection in a 1-year-old female spayed German Shepherd dog is described. Clinical signs were predominantly associated with fungal pyelonephritis and the organism was cultured from the urine. The dog was treated with itraconazole and later, terbinafine was added. Subsequent antifungal susceptibility testing of the isolate showed it to be resistant to all available antifungal drugs. The dog was euthanased because of acute abdominal haemorrhage and associated clinical deterioration. Postmortem examination revealed extensive pyogranulomas containing fungal organisms in the renal parenchyma, myocardium, bone marrow, skeletal muscle, liver, lung, spleen, multiple lymph nodes and pancreas.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22256983/