Peer-reviewed veterinary case report
DNA and DNA + Histone Hydrolysis by Guinea Pig Epidermal Enzymes
- Journal:
- Dermatologica
- Year:
- 2009
- Authors:
- Miyagawa, Teruo & Urabe, Harukuni
- Species:
- rodent
Abstract
An acid deoxyribonuclease of guinea pig epidermis hydrolyzes chromatin DNA as well as histone-free DNA. The enzyme degrades approximately 50% of chromatin DNA, while it degrades 90% of histone-free DNA. Guinea pig epidermal extract contains proteolytic activity for histone or chromatin with a pH optimum at around 8.0.
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Search related cases →Original publication: https://doi.org/10.1159/000251145