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Peer-reviewed veterinary case report

Do early MRI signals predict lesion size in a neonatal stroke rat model?

Journal:
AJNR. American journal of neuroradiology
Year:
2013
Authors:
Fau, S et al.
Affiliation:
CNRS 7102 · France
Species:
rodent

Abstract

In this study, we compared lesion size by using VADC and VT2 at 0, 2, 5, 24, and 48 hours and histologic lesions at 48 hours in a P7 rat stroke model. The best correlation between VHISTO and VADC was at H0, and between VHISTO and VT2, at H2-H5. Early MR imaging signals allowed excluding "no-lesion" and "no-reflow" animals to help standardize this neonatal stroke model and predict lesion size.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22555584/