Peer-reviewed veterinary case report
Dog developed slow heart rate after dobutamine during surgery
By Hofmeister, Erik H et al.·Published in Veterinary anaesthesia and analgesia·2005·Department of Large Animal Medicine, United States·View original on PubMed →
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Original publication title: Dobutamine-induced bradycardia in a dog.
- Species:
- dog
Plain-English summary
An 8-year-old neutered male mixed breed dog was undergoing surgery to remove bladder stones when he developed a dangerously low heart rate after receiving a medication called dobutamine. The vet quickly treated this by giving him atropine, which successfully increased his heart rate back to normal. The drop in heart rate was likely due to a reflex response from his nervous system triggered by the medication. The vet advised that if this happens again during treatment, they should stop the dobutamine or use a medication to counteract the effect.
People also search for: dog surgery heart rate drop · dobutamine side effects in dogs · atropine for dog bradycardia
Abstract
An otherwise healthy 8-year-old neutered male, mixed breed dog was anesthetized for surgical removal of multiple uroliths. Pre-anesthetic medication was midazolam, glycopyrrolate, and morphine. Anesthesia was induced with propofol and maintained with isoflurane in oxygen. One hour after induction, the patient moved and propofol was administered. Subsequently, the patient developed hypotension. Dobutamine administered at this time produced a rapid and profound decrease in heart rate that was treated successfully with atropine. The bradycardia in this case may be the result of the Bezold-Jarisch reflex, an intracardiac parasympathetic nervous reflex. Discontinuation of dobutamine and/or administration of a parasympatholytic drug should be performed if bradycardia occurs during dobutamine infusion.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15762916/