Peer-reviewed veterinary case report
How long vaccines protect dogs from common viruses in Australia
By Mitchell, SA et al.·Published in Australian Veterinary Journal·2012·Pfizer Animal Health 38–42 Wharf Road West Ryde New South Wales 2114 Australia, United Kingdom·View original on Crossref →
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Original publication title: Duration of serological response to canine parvovirus‐type 2, canine distemper virus, canine adenovirus type 1 and canine parainfluenza virus in client‐owned dogs inAustralia
- Species:
- dog
Plain-English summary
A group of dogs in Australia, who hadn't been vaccinated in over 18 months, were tested to see if they still had immunity against several serious viruses, including canine parvovirus and canine distemper. After revaccination, nearly all the dogs showed a strong immune response, indicating that the vaccines were still effective even after a long time. This suggests that the immunity from these vaccines can last much longer than previously thought, possibly up to 9 years. As a result, veterinarians may consider extending the time between vaccinations for these diseases.
People also search for: dog vaccination schedule · how long does dog vaccine last · canine parvovirus vaccine effectiveness
Abstract
ObjectiveTo determine whether client‐owned dogs in Australia, last vaccinated withCanvac® vaccines containing canine parvovirus‐type 2 (CPV‐2), canine distemper virus (CDV), canine adenovirus type 2 (CAV‐2) ± canine parainfluenza virus (CPiV) at least 18 months ago, were seropositive or responded serologically to revaccination.MethodsA total of 235 dogs were recruited from 23 veterinary clinics, representing a variety of breeds, ages and time since last vaccination (TSLV: range 1.5–9 years, mean 2.8 years). Dogs had a blood sample taken and were revaccinated on day 0. A second blood sample was taken 7–14 days later. Blood samples were assessed for antibody titres toCPV‐2 (by haemagglutination inhibition) andCDV,CAVtype 1 (CAV‐1) and CPiV (by virus neutralisation). Dogs with a day 0 titre >10 or a four‐fold increase in titre following revaccination were considered to be serological responders.ResultsThe overall percentage of dogs classified as serological responders was 98.7% forCPV‐2, 96.6% forCDV, 99.6% forCAV‐1 and 90.3% forCPiV.ConclusionsThese results suggest that the duration of serological response induced by modified‐live vaccines againstCPV‐2,CDV,CAV‐1 andCPiV, includingCanvac® vaccines, is beyond 18 months and may extend up to 9 years. Accordingly, these vaccines may be considered for use in extended revaccination interval protocols as recommended by current canine vaccine guidelines.
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/j.1751-0813.2012.01009.x