Peer-reviewed veterinary case report
How long vaccines protect dogs from parvovirus and distemper
By Mitchell, S A et al.·Published in Australian veterinary journal·2012·Pfizer Animal Health, United Kingdom·View original on PubMed →
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Original publication title: Duration of serological response to canine parvovirus-type 2, canine distemper virus, canine adenovirus type 1 and canine parainfluenza virus in client-owned dogs in Australia.
- Species:
- dog
Plain-English summary
A group of dogs in Australia, who had not been vaccinated for at least 18 months, were tested for their immunity against several serious viruses, including canine parvovirus and canine distemper virus. After revaccination, nearly all the dogs showed a strong immune response, with 98.7% responding to parvovirus and 96.6% to distemper. This suggests that the vaccines can provide protection for much longer than previously thought, possibly up to 9 years. Pet owners can feel reassured that their dogs are likely still protected even if they haven't been vaccinated recently.
People also search for: dog vaccination schedule · how long does dog vaccine last · canine parvovirus vaccine effectiveness
Abstract
OBJECTIVE: To determine whether client-owned dogs in Australia, last vaccinated with Canvac(®) vaccines containing canine parvovirus-type 2 (CPV-2), canine distemper virus (CDV), canine adenovirus type 2 (CAV-2) ± canine parainfluenza virus (CPiV) at least 18 months ago, were seropositive or responded serologically to revaccination. METHODS: A total of 235 dogs were recruited from 23 veterinary clinics, representing a variety of breeds, ages and time since last vaccination (TSLV: range 1.5-9 years, mean 2.8 years). Dogs had a blood sample taken and were revaccinated on day 0. A second blood sample was taken 7-14 days later. Blood samples were assessed for antibody titres to CPV-2 (by haemagglutination inhibition) and CDV, CAV type 1 (CAV-1) and CPiV (by virus neutralisation). Dogs with a day 0 titre >10 or a four-fold increase in titre following revaccination were considered to be serological responders. RESULTS: The overall percentage of dogs classified as serological responders was 98.7% for CPV-2, 96.6% for CDV, 99.6% for CAV-1 and 90.3% for CPiV. CONCLUSIONS: These results suggest that the duration of serological response induced by modified-live vaccines against CPV-2, CDV, CAV-1 and CPiV, including Canvac(®) vaccines, is beyond 18 months and may extend up to 9 years. Accordingly, these vaccines may be considered for use in extended revaccination interval protocols as recommended by current canine vaccine guidelines.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23186088/