Peer-reviewed veterinary case report
Using dynamic contrast MRI to diagnose brain tumors in dogs
By Choi, Simon et al.·Published in Frontiers in veterinary science·2024·Veterinary Referral Hospital, Australia·View original on PubMed →
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Original publication title: Dynamic contrast enhanced high field magnetic resonance imaging for canine primary intracranial neoplasia.
- Species:
- dog
Plain-English summary
A group of dogs with brain tumors underwent a special MRI technique to help identify whether they had meningiomas, a type of tumor, or other types of brain tumors. The study found that dogs with meningiomas had higher blood flow in their tumors compared to those with different types of brain tumors. This information could help veterinarians make better treatment decisions for dogs diagnosed with these conditions. While the study showed promising results, further research is needed to confirm these findings.
People also search for: dog brain tumor symptoms · meningioma treatment for dogs · MRI for dog brain problems
Abstract
INTRODUCTION: Distinguishing meningiomas from other intracranial neoplasms is clinically relevant as the prognostic and therapeutic implications differ greatly and influence clinical decision making. Dynamic contrast-enhanced MRI (DCE-MRI) is an imaging technique that assists with characterisation of physiologic alterations such as blood flow and tissue vascular permeability. Quantitative pharmacokinetic analysis utilising DCE-MRI has not been studied in canine neuro-oncology. METHODS: A retrospective study was performed in canine patients that underwent DCE-MRI with an imaging diagnosis of an intracranial meningioma and surgery for histopathological diagnosis. Kinetic parameters Ktrans and cerebral blood flow were measured and compared to assess whether differences could be identified between meningiomas and other intracranial neoplasms. RESULTS: Six dogs with meningiomas and 3 dogs with other intracranial neoplasms were included for statistical analysis. Cerebral blood flow values were found to be statistically higher within meningiomas compared to other intracranial neoplasms. Ktrans values were higher within meningiomas than in other types of intracranial tumours, however this difference did not reach statistical significance. DISCUSSION: Based on the results of this study cerebral blood flow measurement can be utilised to differentiate canine intracranial meningiomas from other similar appearing intracranial tumours.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39430382/