Peer-reviewed veterinary case report
Right heart function in dogs with mitral valve disease stages
By Chapel, E H et al.·Published in Journal of veterinary internal medicine·2018·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Echocardiographic Estimates of Right Ventricular Systolic Function in Dogs with Myxomatous Mitral Valve Disease.
- Species:
- dog
Plain-English summary
A group of 36 dogs with myxomatous mitral valve disease (MMVD), a common heart issue in pets, were studied to see how their right ventricle function changed with the severity of their condition. The dogs were divided into three groups based on their disease stage, and it was found that those in stage B2 had better right ventricular function compared to those in the more severe stage C. This suggests that monitoring right ventricular function, especially using a measurement called TAPSE, could help veterinarians assess the health of dogs with MMVD and predict their outcomes.
People also search for: dog heart disease symptoms · myxomatous mitral valve disease in dogs · TAPSE measurement in dogs with heart problems
Abstract
BACKGROUND: Right ventricular (RV) dysfunction independently predicts outcomes in human myxomatous mitral valve disease (MMVD). There is limited information regarding RV systolic function in dogs with MMVD. HYPOTHESIS: Right ventricular systolic function differs among stages of disease, decreasing in decompensated MMVD. ANIMALS: Thirty-sixclient-owned dogs with MMVD not receiving oral cardiovascular medications. METHODS: Prospective clinical study. Dogs were categorized according to disease severity as ACVIM Stage B1, B2, or C. Seven echocardiographic indices of RV systolic function were measured. Groups were compared by 1-way ANOVA and Tukey's HSD test. Frequencies of cases with cardiac remodeling falling outside previously established reference intervals were compared using Fisher's exact test. Intra- and interobserver measurement variability was calculated for each RV function index. RESULTS: The indices TAPSE (P = 0.029), RV St(P = 0.012), and RV StR(P = 0.041) were significantly different between groups. A greater proportion of B2 dogs (7 of 12) had TAPSE values above reference intervals compared with B1 (2 of 12) or C (2 of 12) dogs (P = 0.027). Measurement variability of TAPSE, RV S', and RV Stwas clinically acceptable. CONCLUSIONS AND CLINICAL IMPORTANCE: Right ventricular systolic function differs between stages of MMVD, increasing in stage B2, and declining in stage C. The prognostic importance of RV function indices, particularly TAPSE, might be worth evaluating in dogs with MMVD.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29224256/