Peer-reviewed veterinary case report
High phosphorus diet causes kidney stress signs in healthy cats
By Dobenecker, Britta et al.·Published in Journal of feline medicine and surgery·2018·Department of Veterinary Sciences, Germany·View original on PubMed →
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Original publication title: Effect of a high phosphorus diet on indicators of renal health in cats.
- Species:
- cat
Plain-English summary
A group of healthy adult cats was fed a diet high in phosphorus for 29 days to see how it affected their kidney health. The cats on this high phosphorus diet showed signs of kidney stress, including increased levels of glucose and protein in their urine, which were not present in the cats on a balanced diet. Additionally, their kidney function, measured by creatinine clearance, decreased significantly. This study suggests that feeding cats a diet with too much phosphorus can negatively impact their kidney function, even in healthy animals.
People also search for: cat kidney health diet · high phosphorus diet effects in cats · signs of kidney disease in cats
Abstract
Objectives High phosphorus intake may further impair renal health in cats with chronic kidney disease (CKD). The hypothesis that a high phosphorus (HP) diet might be nephrotoxic for healthy animals was tested in cats, a species with a high incidence of naturally occurring CKD. Methods Thirteen healthy adult cats were fed a phosphorus excess diet (about five times maintenance requirements), and this HP group was compared with cats on a balanced control diet (CON). The trial lasted for 29 days (10 days of faeces and urine collection). Endogenous creatinine clearance was determined towards the end of the trial. Fresh urine was tested for glucose and proteins. Results Glucosuria and microalbuminuria were observed exclusively in the HP group in 9/13 cats. Creatinine clearance was significantly decreased after feeding HP. In the HP group phosphorus was highly available (apparent digestibility around 60%). Renal phosphorus excretion was significantly increased in the HP group (115 mg/kg body weight/d vs 16 mg/kg body weight/d in the CON group). Conclusions and relevance The intake of a diet with an excessive content of highly available phosphorus may have adverse effects on parameters of kidney function in healthy cats.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28569079/