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Peer-reviewed veterinary case report

Stem cell therapy improves lameness in dogs with chronic hip arthritis

By Black, Linda L et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2007·Vet-Stem, United States·View original on PubMed

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Original publication title: Effect of adipose-derived mesenchymal stem and regenerative cells on lameness in dogs with chronic osteoarthritis of the coxofemoral joints: a randomized, double-blinded, multicenter, controlled trial.

Species:
dog

Plain-English summary

A group of dogs with chronic hip arthritis were treated with stem cells taken from their own fat to see if it would help their limping and pain. The dogs that received the stem cell therapy showed significant improvements in their ability to move and had less pain compared to those that did not receive the treatment. This study is the first of its kind to confirm that stem cell therapy can be effective for dogs suffering from osteoarthritis in their hips.

People also search for: dog limping treatment · stem cell therapy for dog arthritis · hip pain in dogs · how to help dog with osteoarthritis

Abstract

Autologous stem cell therapy in the field of regenerative veterinary medicine involves harvesting tissue, such as fat, from the patient, isolating the stem and regenerative cells, and administering the cells back to the patient. Autologous adipose-derived stem cell therapy has been commercially available since 2003, and the current study evaluated such therapy in dogs with chronic osteoarthritis of the hip. Dogs treated with adipose-derived stem cell therapy had significantly improved scores for lameness and the compiled scores for lameness, pain, and range of motion compared with control dogs. This is the first randomized, blinded, placebo-controlled clinical trial reporting on the effectiveness of stem cell therapy in dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18183546/