Peer-reviewed veterinary case report
Platelet rich fibrin helps knee cartilage heal in dogs
By Kazemi, Davoud et al.·Published in BioMed research international·2014·Department of Veterinary Clinical Sciences·View original on PubMed →
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Original publication title: Effect of autologous platelet rich fibrin on the healing of experimental articular cartilage defects of the knee in an animal model.
- Species:
- dog
Plain-English summary
A group of 12 mixed breed dogs had cartilage damage in their knees created for a study. One knee in each dog was treated with a special product made from their own blood called platelet rich fibrin (PRF), while the other knee was left untreated. After several weeks, the dogs were examined, and the results showed that the knees treated with PRF had better healing compared to those that weren't treated. This suggests that using PRF could help improve recovery from cartilage injuries in dogs.
People also search for: dog knee cartilage injury treatment · platelet rich fibrin for dogs · dog knee pain recovery
Abstract
The effect of autologous platelet rich fibrin (PRF), a second generation platelet product, on the healing of experimental articular cartilage lesions was evaluated in an animal model. Full thickness cartilage lesions with a diameter of 6 mm and depth of 5 mm were created in the weight bearing area of femoral condyles of both hind limbs in 12 adult mixed breed dogs. Defects in the left hind limb of each dog were repaired by PRF implantation whereas those in the right hind limb were left empty. The animals were euthanized at 4, 16, and 24 weeks following surgery and the resultant repair tissue was investigated macroscopically and microscopically. The results of macroscopic and histological evaluations indicated that there were significant differences between the PRF treated and untreated defects. In conclusion, the present study indicated that the use of platelet rich fibrin as a source of autologous growth factors leads to improvement in articular cartilage repair.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25028656/