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Peer-reviewed veterinary case report

Effect of chronic administration of fruit extract (Citrus unshiu Marc.) on glucose tolerance in GK rats, a model of type 2 diabetes.

Journal:
Bioscience, biotechnology, and biochemistry
Year:
2006
Authors:
Sugiura, Minoru et al.
Affiliation:
Department of Citrus Research · Japan
Species:
rodent

Abstract

Recent epidemiological studies have demonstrated that high dietary consumption of fruit and vegetables results in lower risks of diabetes. In this study, we investigated the effects of chronic administration of fruit extract (Citrus unshiu Marc.) on glucose tolerance in GK rats, a model of type 2 diabetes. After 10 weeks administration of the fruit extract, intraperitoneal glucose tolerance tests revealed significant decrements of blood glucose levels after glucose loading. Our findings further support an advantageous association of fruit consumption with diabetes.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16428854/