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Peer-reviewed veterinary case report

Effects of ciclosporin and steroids on cats with feline herpesvirus

By Lappin, Michael R & Roycroft, Linda M·Published in Journal of feline medicine and surgery·2015·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Effect of ciclosporin and methylprednisolone acetate on cats previously infected with feline herpesvirus 1.

Species:
cat

Plain-English summary

A group of cats that had previously been infected with feline herpesvirus 1 (FHV-1) were treated with either ciclosporin (a medication to reduce inflammation) or methylprednisolone acetate (a steroid) to see how they would respond. While some cats showed mild signs of respiratory issues, most recovered without serious problems and did not experience any severe symptoms like vomiting or loss of appetite. The treatments were generally well-tolerated, and the cats did not suffer any significant side effects.

People also search for: cat respiratory problems treatment · feline herpesvirus 1 symptoms · ciclosporin for cats · cat upper respiratory infection care

Abstract

Feline herpesvirus 1 (FHV-1) is a common ocular and respiratory pathogen of cats that can be associated with recurrent clinical signs of disease. Ciclosporin (cyclosporine) is commonly administered per os (PO) for the treatment of a number of inflammatory diseases in cats. A number of client-owned cats administered ciclosporin (cyclosporine) A (CsA) PO to block renal transplant rejection have developed clinical signs of upper respiratory tract disease that may have been from activated FHV-1. In this study, cats experimentally inoculated with FHV-1 several months previously were administered methylprednisolone acetate intramuscularly, CsA PO or a placebo PO. While clinical signs of activated FHV-1 occurred in some cats, disease was mild and self-limited in most cats. There was no vomiting, diarrhea, inappetence, weight loss, polydipsia, polyuria or polyphagia recognized.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25204453/