Peer-reviewed veterinary case report
Effect of corosolic acid on the hydrolysis of disaccharides.
- Journal:
- Journal of nutritional science and vitaminology
- Year:
- 2008
- Authors:
- Takagi, Satoshi et al.
- Affiliation:
- Department of Clinical Nutrition · Japan
- Species:
- rodent
Abstract
The banaba leaf (Lagerstroemia speciosa L.) has been used in traditional Oriental medicine to treat diabetes in the Philippines. It contains corosolic acid (CA), a compound which has a hypoglycemic effect. We examined the effect of CA on blood glucose levels and the hydrolysis of disaccharides in the small intestine in mice. CA (10 mg/kg body weight) improved hyperglycemia after an oral administration of sucrose, and significantly reduced the hydrolysis of sucrose in the small intestine. These results suggest that the hypoglycemic activity of CA is derived, at least in part, due to the inhibition of the hydrolysis of sucrose.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/18635916/