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Peer-reviewed veterinary case report

Tylosin and diet changes help chronic diarrhea in beagles

By Westermarck, Elias et al.·Published in Journal of veterinary internal medicine·2005·Department of Clinical Veterinary Sciences·View original on PubMed

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Original publication title: Effect of diet and tylosin on chronic diarrhea in beagles.

Species:
dog

Plain-English summary

Seven beagles suffering from chronic diarrhea for over a month were treated with a medication called tylosin, which helped firm up their stools but didn’t completely resolve the issue. After switching their diet to a dry food designed for adult dogs, their feces improved further, although some still experienced loose stools. When tylosin was given again after a few months, the dogs' feces became significantly firmer and stayed that way during follow-up. This suggests that combining a special diet with tylosin can be more effective for managing chronic diarrhea in dogs than using either treatment alone.

People also search for: beagle chronic diarrhea treatment · tylosin for dog diarrhea · dog diet for loose stools

Abstract

Seven beagles in a colony of dogs had chronic diarrhea for at least 30 days. The dogs were subsequently treated with tylosin 20 mg/kg BW q24h PO for 10 days. During the treatment period, the feces became firmer but remained loose. When the treatment was discontinued, the diarrhea reappeared in 3 weeks. The feces remained abnormally loose in all dogs treated with metronidazole, trimethoprim-sulfadiazine, or doxycycline and prednisone. The diet was then changed for 10 days from a highly digestible moist pet food to a dry food developed for normal adult dogs. The feces again became firmer, although still loose in some dogs. The period was then extended to 3 month, but the fecal consistency continued to fluctuate from ideal to diarrhea. The dogs were treated a 2nd time with tylosin 20 mg/kg BW q24h PO for 10 days. The feces then became significantly firmer and remained so throughout a 3-month follow-up. We conclude that the combination of diet and tylosin was more effective than either agent alone in control of chronic diarrhea.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16355675/