Peer-reviewed veterinary case report
Effect of head-down hanging on the course of degenerative process in the hind paw muscles of 12-month-old MDX mice.
- Journal:
- Bulletin of experimental biology and medicine
- Year:
- 2006
- Authors:
- Tarakin, P P et al.
- Affiliation:
- Institute of Biomedical Problems
- Species:
- rodent
Abstract
Effect of functional unloading on the course of degenerative process in muscles was studied in dystrophin-deficient mdx mice. Head down-hanging of animals led to a significant decrease in the cross-section area of muscle fibers, increase in the percentage of fibers with centrally located nuclei and of Evans blue-stained fibers. Gravitation unloading of 12-month-old animals with pronounced manifestations of muscular dystrophy did not inhibit this pathological process.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17364067/