Peer-reviewed veterinary case report
Stem cell injection helps dogs with chronic elbow arthritis signs
By Black, Linda L et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2008·Vet-Stem Inc., United States·View original on PubMed →
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Original publication title: Effect of intraarticular injection of autologous adipose-derived mesenchymal stem and regenerative cells on clinical signs of chronic osteoarthritis of the elbow joint in dogs.
- Species:
- dog
Plain-English summary
A group of 14 dogs with chronic elbow arthritis (osteoarthritis) received an injection of their own fat-derived stem cells to help reduce pain and improve movement. Veterinarians evaluated the dogs for lameness, pain, and how well they could use their legs before and after the treatment. The results showed that the dogs experienced significant improvement in their symptoms, including less pain and better mobility, lasting up to 180 days after the injection. This treatment could be a promising option for dogs suffering from elbow arthritis.
People also search for: dog elbow arthritis treatment · stem cell therapy for dogs · how to help my dog with joint pain
Abstract
Autologous adipose-derived mesenchymal stem cell (AD-MSC) therapy involves harvesting fat from the patient, isolating the stem and regenerative cells, and administering the cells back to the patient. Autologous AD-MSC therapy in veterinary regenerative medicine has been commercially available since 2003. Previously reported results from a blinded, controlled trial in dogs with chronic osteoarthritis of the coxofemoral (hip) joint demonstrated efficacy of a single intraarticular injection of autologous AD-MSC therapy. The primary objective of the current study was to evaluate the effectiveness of this therapy in dogs with chronic osteoarthritis of the humeroradial (elbow) joints and to determine the duration of effect. Fourteen dogs were recruited. Veterinarians assessed each dog for lameness, pain on manipulation, range of motion, and functional disability using a numeric rating scale at baseline and specified intervals up to 180 days after treatment. Statistically significant improvement in outcome measures was demonstrated.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19003780/