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Peer-reviewed veterinary case report

Effect of eye epinephrine on heart rate and pressure after dog

By Osinchuk, Stephanie C et al.·Published in Veterinary ophthalmology·2020·Department of Small Animal Clinical Science, Canada·View original on PubMed

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Original publication title: Effect of intracameral epinephrine on heart rate, post-operative ocular hypertension, and long-term outcome following canine phacoemulsification.

Species:
dog

Plain-English summary

A group of 30 dogs undergoing cataract surgery (phacoemulsification) were given either a solution containing epinephrine or a saline solution during the procedure. After surgery, both groups experienced some increase in eye pressure, but there was no significant difference between the two treatments. Complications were also less common in the epinephrine group compared to the saline group, though the difference wasn't significant. Overall, using epinephrine during surgery was found to be safe and may help reduce some post-operative issues.

People also search for: dog cataract surgery complications · canine phacoemulsification recovery · eye pressure after dog surgery

Abstract

PURPOSE: To determine the effect of intrsacameral epinephrine on heart rate, blood pressure, post-operative ocular hypertension, and complications following canine phacoemulsification. PROCEDURES: A prospective, double-blinded, controlled trial was carried out using 30 client-owned dogs undergoing phacoemulsification. Eyes were randomly assigned to a treatment group receiving intracameral (IC) epinephrine (n = 31) or balanced salt solution (n = 25) at the beginning of surgery. Heart rate, post-operative intraocular pressures, and outcomes were compared between treatment groups. RESULTS: No adverse reactions to IC epinephrine or saline were observed. Post-operative ocular hypertension developed at the 2 and/or 4 hours pressure reading in 35% and 46% in the epinephrine and saline groups, respectively (P = .5072). There were 9.7% and 23.1% eyes that developed complications in the IC epinephrine and saline groups, respectively (P = .2373). CONCLUSIONS: Intracameral epinephrine is safe to use, and non-significant decreases in post-operative ocular hypertension and long-term complications were observed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32813935/