Peer-reviewed veterinary case report
Platelet-rich plasma injections improve leg use in bulldogs with knee
By Vilar, José M et al.·Published in PloS one·2018·Departamento de Patologí, Spain·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Effect of leukocyte-reduced platelet-rich plasma on osteoarthritis caused by cranial cruciate ligament rupture: A canine gait analysis model.
- Species:
- dog
Plain-English summary
Twelve English bulldogs with limping due to knee problems from a torn cranial cruciate ligament were treated with four injections of platelet-rich plasma (PRP) over three months. Owners noticed improvements in their dogs' ability to bear weight and move more freely after the treatment, with noticeable changes in their gait and comfort levels. However, the benefits started to decrease after three months and returned to near their original state by six months. This suggests that while PRP can help with joint issues, the effects may not last long-term.
People also search for: English bulldog limping treatment · PRP injections for dog arthritis · torn cruciate ligament recovery in dogs
Abstract
The goal of this study was to objectively assess the effect of a platelet-rich plasma (PRP) derivate in English bulldogs with stifle degenerative joint disease secondary to cranial cruciate ligament rupture (CCLR). We used a force platform and affixed electrogoniometers to measure peak vertical force (PVF), vertical impulse (VI), stance time (ST), and angular range of motion (AROM), from 12 lame client-owned English bulldogs with post-CCLR stifle joint abnormalities. The 12 affected subjects were treated with 4 intra-articular injections of PRP, at 30-day intervals. Ten untreated, sound English bulldogs were used as a reference group. Clinical outcomes were evaluated using a linear mixed effects model. Mean values of PVF, VI, ST, and AROM were improved within the first 3 months post-treatment in the CCLR group, with mean measured changes increasing to maximum 4.56% body weight gain, 1.5% body weight/second, 0.07 seconds, and 6.18 degrees, respectively. The effects declined progressively after the treatment interval, ending at nearly initial levels after 6 months. This study demonstrates that dogs with CCLR treated with intra-articular PRP had improved PVF, VI, ST, and AROM over time; the duration of effect was waning by the end of the post-treatment period.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29554150/