Peer-reviewed veterinary case report
Oral hydrocortisone does not raise eye pressure in dogs
By Herring, Ian P et al.·Published in Veterinary ophthalmology·2004·Department of Small Animal Clinical Sciences Virginia Polytechnic Institute and State University, United States·View original on PubMed →
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Original publication title: Effect of orally administered hydrocortisone on intraocular pressure in nonglaucomatous dogs.
- Species:
- dog
Plain-English summary
A group of 17 dogs with normal eye pressure were given either hydrocortisone or a placebo for five weeks to see if it would affect their eye pressure. The results showed that while eye pressure increased in both groups over time, the hydrocortisone did not significantly change the eye pressure compared to the placebo. This means that hydrocortisone is safe to use in these dogs without worrying about raising their eye pressure.
People also search for: dog eye pressure treatment · hydrocortisone for dogs · why is my dog’s eye pressure increasing
Abstract
OBJECTIVE: To determine the effect of oral hydrocortisone on intraocular pressure (IOP) in ocular normotensive dogs. ANIMALS STUDIED: Seventeen ocular normotensive dogs. Procedures Dogs were randomly assigned to treatment (n = 9) and control (n = 8) groups. Dogs in the treatment group received hydrocortisone, 3.3 mg/kg PO every 8 h, and dogs in the control group received gelatin capsule placebo PO every 8 h for 5 weeks. Applanation tonometry was performed on both eyes of all dogs prior to treatment and then once weekly for 5 weeks during hydrocortisone treatment. RESULTS: No significant effect of treatment was noted for right (P = 0.1013) or left (P = 0.1157) eyes during the treatment period, nor was there significant interaction of treatment by week for the right (P = 0.9456) or left (P = 0.3577) eyes. A significant rise in IOP over the treatment period was noted in both right (P < 0.0001) and left (P = 0.0006) eyes of both groups, but was unrelated to treatment. CONCLUSION: Orally administered hydrocortisone does not significantly increase IOP in nonglaucomatous dogs when administered over a 5-week period.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15511278/