Peer-reviewed veterinary case report
Vitamin E and selenium boost immune response in dogs vaccinated
By Kandil, Omnia M & Abou-Zeina, Hala A A·Published in Journal of the Egyptian Society of Parasitology·2005·Department of Parasitology and Animal Diseases·View original on PubMed →
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Original publication title: Effect of parenteral vitamin E and selenium supplementation on immune status of dogs vaccinated with subunit and somatic antigens against Taenia hydatigena.
- Species:
- dog
Plain-English summary
Thirty healthy dogs were given vaccines to protect against a parasite called Taenia hydatigena, with some also receiving vitamin E and selenium supplements. The dogs that received the supplements showed a stronger immune response, producing more antibodies compared to those that didn't get the extra nutrients. The best protection was seen in the groups that received the subunit vaccine along with the supplements, with an 83.3% success rate in preventing infection. This suggests that adding vitamin E and selenium can boost the effectiveness of certain vaccines in dogs.
People also search for: dog vaccine effectiveness · vitamin E selenium for dogs · Taenia hydatigena prevention in dogs
Abstract
Thirty clinically healthy dogs were divided into five equal groups; Gs 1 and 2 were vaccinated with subunit and somatic antigens (Ags) respectively in combination with vitamin E and selenium (Vit E/Se) supplement, Gs 3 and 4 were vaccinated with subunit and somatic Ags respectively and group 5 was kept unvaccinated as control positive. Dogs in the vaccinated-Vit E/Se supplemented groups had a significantly greater (P < 0.05) serum Se and alpha-tocopherol than un-supplemented Gs. Best immune response against T. hydatigena was observed in the Vit E/Se supplemented groups, as evidenced by increase production of antibody titer and IgG concentration in comparison with either vaccinated un-supplemented or control groups. Moreover, the highest protection level against T. hydatigena infection was observed in groups 1 and 2 (83.3%), while was 66.7% and 50% in groups 3 and 4 respectively. Subunit Ag was more efficient than somatic Ag in improving the immune status of dogs. Vit E and Se proved to be immuno-potentiating to dogs vaccinated with subunit and somatic Ags and increased the possibility for the protection against T. hydatigena infection.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16083066/