Peer-reviewed veterinary case report
How abdominal washing affects bacteria in dogs with septic peritonitis
By Marshall, Hannah et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2019·Angell Animal Medical Center, United States·View original on PubMed →
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Original publication title: Effect of peritoneal lavage on bacterial isolates in 40 dogs with confirmed septic peritonitis.
- Species:
- dog
Plain-English summary
A group of 40 dogs with septic peritonitis (a serious abdominal infection) underwent surgery and received a special washing treatment called peritoneal lavage to help clear the infection. After the treatment, 87.5% of the dogs were able to go home from the hospital. The lavage significantly reduced the chances of finding bacteria that were resistant to multiple antibiotics, which is a positive outcome for treatment. Most dogs received the right antibiotics based on culture results, and while a few did not survive, the overall survival rate was better than what has been seen in other studies.
People also search for: dog septic peritonitis treatment · peritoneal lavage for dogs · dog abdominal infection antibiotics
Abstract
OBJECTIVE: To evaluate bacterial isolates, antimicrobial drug susceptibility, and change in resistance among pre- and post-lavage culture samples in dogs with septic peritonitis. DESIGN: Prospective observational study. SETTING: Private practice referral hospital. ANIMALS: Forty client-owned dogs with confirmed septic peritonitis requiring surgical intervention. INTERVENTIONS: All dogs had perioperative abdominal lavage following source control with 200 to 300 mL/kg 0.9% sterile saline. Pre- and post-lavage aerobic and anaerobic culture samples were evaluated. MEASUREMENTS AND MAIN RESULTS: Thirty-five of 40 dogs (87.5%) survived to hospital discharge. The likelihood of an aerobic organism to have multidrug resistance (resistance to 3 or more antimicrobial classes) post-lavage was a third of that pre-lavage (odds ratio [OR] 0.34, 95% CI [0.17-0.68], P = 0.01). Thirty-nine of 40 dogs (97.5%) received appropriate empiric antimicrobial therapy based on pre- and post-lavage culture results, of which 5 (12.8%) did not survive to discharge. The single dog with inappropriate antimicrobial therapy survived to discharge. The most frequent isolates detected included Escherichia coli, Clostridium perfringens, and Enterococcus faecalis. The same organism based on species was isolated in pre- and post-lavage cultures in 32 dogs, accounting for 59 anaerobic and aerobic isolates. There was a new bacterial isolate detected in 20 dogs, accounting for 46 isolates and an overall total decrease of 14 isolates between pre- and post-lavage culture (P = 0.09). CONCLUSIONS: This study suggests that there is a significant decrease in the likelihood of isolating a multidrug resistant organism following peritoneal lavage, and aerobic and anaerobic culture results have the potential to change following peritoneal lavage, although this cannot be confirmed without further studies. Overall survival rates were higher than previously reported in the literature for septic peritonitis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31637851/