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Peer-reviewed veterinary case report

Effect of preoperative administration of tepoxalin on hemostasis and hepatic and renal function in dogs.

Journal:
Veterinary therapeutics : research in applied veterinary medicine
Year:
2004
Authors:
Kay-Mugford, Patricia A et al.
Affiliation:
Schering-Plough Animal Health · United States
Species:
dog

Abstract

Preemptive analgesia is an important part of surgical management, but some NSAIDs can adversely affect platelet function or renal or hepatic status. Tepoxalin is approved in the United States for control of pain and inflammation associated with arthritis and in Europe for relief of pain caused by musculoskeletal disorders. In this study, no significant effects on indices of hemostasis or renal or hepatic function were detected when a single preoperative oral dose of tepoxalin was administered to young healthy dogs undergoing anesthesia and surgery.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15468009/