Peer-reviewed veterinary case report
Effect of Renshen polysaccharides on oxidative injury in kidney IR rabbits.
- Journal:
- Carbohydrate polymers
- Year:
- 2012
- Authors:
- Liu, Zhangshun et al.
- Affiliation:
- Department of Urology · China
- Species:
- rabbit
Abstract
There is increasing evidence to suggest that reactive oxygen metabolites (ROMs) play a role in the pathogenesis of ischemia/reperfusion (I/R) injury in the kidney. This study was designed to determine the possible protective effect of Renshen polysaccharides (RSP) on renal ischemia/reperfusion (I/R) injury. Results showed that the polysaccharides of Renshen consisted mainly of glucose (29.21%), mannose (6.54%), rhamnose (4.34%), arabose (6.92%), galactose (18.41%). In addition, kidney lipid peroxidation level in IR rabbits were markedly increased, whereas antioxidant enzymes activities were significantly decreased. Renshen polysaccharides pre-treatment could decrease oxidative injury in kidney of IR rabbits.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22840000/