Peer-reviewed veterinary case report
Best way to test fungal infection in dogs with nasal aspergillosis
By Billen, F et al.·Published in The Journal of small animal practice·2009·Department of Clinical Sciences·View original on PubMed →
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Original publication title: Effect of sampling method and incubation temperature on fungal culture in canine sinonasal aspergillosis.
- Species:
- dog
Plain-English summary
Sixteen dogs with sinonasal aspergillosis (a fungal infection in the nose) were studied to find the best way to collect samples for diagnosis. Researchers took nasal secretions, mucosal biopsies, and fungal plaques from these dogs and found that fungal growth was more successful when samples were incubated at 37 degrees Celsius rather than at room temperature. Specifically, more fungal growth was seen from mucosal biopsies and fungal plaques, making these methods more reliable for diagnosing this condition. This means that if your dog has nasal issues, a biopsy or plaque sample might be the best way to confirm a fungal infection.
People also search for: dog nasal infection treatment · canine sinonasal aspergillosis symptoms · how to diagnose dog fungal infection
Abstract
OBJECTIVES: To evaluate the most appropriate sampling procedure and the effect of incubation temperature on fungal culture in the diagnosis of canine sinonasal aspergillosis (SNA). METHODS: Sixteen dogs with SNA and 20 dogs with non-fungal nasal disease entered a prospective study. Nasal secretions and mucosal biopsies were collected in all dogs. Fungal plaques were also sampled in dogs with SNA. Each specimen was taken in duplicate from each dog and incubated at room temperature and 37 degrees C. RESULTS: In dogs with SNA, nasal secretions, mucosal biopsies and fungal plaques yielded fungal growth at room temperature in one, one and seven dogs, respectively, whereas fungal growth was obtained at 37 degrees C in three, 12 and 14 dogs, respectively. No specimen collected from any dog with non-fungal nasal disease yielded fungal growth at room temperature or at 37 degrees C. CLINICAL SIGNIFICANCE: The diagnosis of canine SNA is more likely to be confirmed following culture of mucosal biopsies or fungal plaques than nasal secretions sampled blindly with swabs. Incubating cultures at 37 degrees C is more likely to provide a diagnostic outcome than when samples are cultured at room temperature. Fungal culture of nasal specimens has good specificity for the diagnosis of SNA in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19037883/