Peer-reviewed veterinary case report
Effect of Standard and High-Fat Diets during Modeling of Streptozotocin-Induced Diabetes in Rats on the Development of Complications.
- Journal:
- Bulletin of experimental biology and medicine
- Year:
- 2021
- Authors:
- Shaykhutdinova, E R et al.
- Affiliation:
- Affiliated Branch of M. M. Shemyakin and Y. A. Ovchinnikov Institute of Bioorganic Chemistry
- Species:
- rodent
Abstract
For evaluation of the effect of high-fat diet on the development of diabetic complications, the rats were maintained on standard or high-fat diet. In 3 weeks, diabetes mellitus was modeled by single intraperitoneal injection of streptozotocin. Changes in hematological parameters, physical and biochemical parameters of the urine, and in the development of thermal allodynia were different after 15-week standard and high-fat diets.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/33893947/