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Peer-reviewed veterinary case report

Effect of supplementation withCNCM I-1079 on vaccine response to an inactivated bacterial vaccine in young Japanese Black calves: A field trial.

Journal:
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire
Year:
2023
Authors:
Mori, Kazusa et al.
Affiliation:
School of Veterinary Medicine · Japan

Abstract

group (SB group) calves were fed 2.0 × 10CFU/day ofin milk replacer after 2 wk of age. All calves received inactivated vaccine for, andat 3 wk of age and 3 wk later. After vaccination, the SB group calves showed significantly higher (mean difference: 1.56-fold) antibody titer againstthan the control group. The number of calves with the antibody titer above the cut-off value forof the SB group was significantly higher than that of the control, and the percentage was twice as high. In addition, the mRNA transcription ofandin peripheral blood mononuclear cells at the booster of the SB group was significantly higher than those of the control. In conclusion,may have positively affected immune responses to the inactivated multi-bacterial vaccine in young calves in the field.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/37397640/